Human PKR protein, His tag, Unconjugated

Catalog Number: GTX00113-PRO
Article Name: Human PKR protein, His tag, Unconjugated
Biozol Catalog Number: GTX00113-PRO
Supplier Catalog Number: GTX00113-pro
Alternative Catalog Number: GTX00113-PRO-10
Manufacturer: GeneTex
Category: Proteine/Peptide
Application: FA
Species Reactivity: Human
Conjugation: Unconjugated
Alternative Names: eukaryotic translation initiation factor 2 alpha kinase 2 , EIF2AK1 , PKR , PPP1R83 , PRKR
NCBI: 5610
UniProt: P19525
Buffer: Reconstitute with 20mM Tris and 150mM NaCl to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris, 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
Expression System: E. coli
Form: Lyophilized powder
Sequence: N-terminal His-Tag, Ser224~Ile502 (NP_001129123.1)
Application Notes: Protein Kinase R (PKR) is activated by double-stranded RNA (dsRNA), the synthesis of which is caused virally. PKR can also be activated by the protein PACT or by heparin. It plays a key role in the innate immune response to viral infection and is also in