Human MDM2 protein, His tag, Unconjugated

Catalog Number: GTX00176-PRO
Article Name: Human MDM2 protein, His tag, Unconjugated
Biozol Catalog Number: GTX00176-PRO
Supplier Catalog Number: GTX00176-pro
Alternative Catalog Number: GTX00176-PRO-10
Manufacturer: GeneTex
Category: Proteine/Peptide
Application: FA
Species Reactivity: Human
Conjugation: Unconjugated
Alternative Names: MDM2 proto-oncogene , ACTFS , HDMX , hdm2
NCBI: 4193
UniProt: Q00987
Buffer: Reconstitute with 20mM Tris and 150mM NaCl to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris, 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
Expression System: E. coli
Form: Lyophilized powder
Sequence: N-terminal His-Tag, Met1~Pro218 (NP_001138811.1)
Application Notes: Mouse double minute 2 homolog (MDM2) also known as E3 ubiquitin-protein ligase Mdm2 is a cellular oncoprotein that recognizes the N-terminal trans-activation domain (TAD) of the p53 tumor suppressor and as an inhibitor of p53 transcriptional activation.