This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms
Reconstitute with 20mM Tris (pH8.0) and 150mM NaCl (pH8.0) to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris (pH8.0), 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
Expression System:
E. coli
Form:
Lyophilized powder
Sequence:
N-terminal His-Tag, Ala25~Glu91 (NP_000603.1)
Application Notes:
insulin-like growth factor 2 (IGF2) is one of three protein hormones that share structural similarity to insulin. It has growth-regulating, insulin-like and mitogenic activities. IGF2 exerts its effects by binding to the IGF-1 receptor and to the short i
GTX00213-pro Functional Assay Image
Cell proliferation effect of GTX00213-pro Human IGF2 protein (active). Cell viability was measured by Cell Counting Kit-8 (CCK-8). (A) Unstimulated MCF-7 cells cultured in DMEM for 96hrs. (B) MCF-7 cells cultured in DMEM, stimulated with 1 ng/ml IGF2 for 96hrs.
SDS-PAGE analysis of GTX00213-pro Human IGF2 protein (active).
WB analysis of GTX00213-pro Human IGF2 protein (active).
* VAT and and shipping costs not included. Errors and price changes excepted
