Human Neuregulin-1 protein, His tag (active), Unconjugated

Catalog Number: GTX00417-PRO
Article Name: Human Neuregulin-1 protein, His tag (active), Unconjugated
Biozol Catalog Number: GTX00417-PRO
Supplier Catalog Number: GTX00417-pro
Alternative Catalog Number: GTX00417-PRO-10
Manufacturer: GeneTex
Category: Proteine/Peptide
Application: FA
Species Reactivity: Human
Conjugation: Unconjugated
Alternative Names: neuregulin 1 , ARIA , GGF , GGF2 , HGL , HRG , HRG1 , HRGA , MST131 , MSTP131 , NDF , NRG1-IT2 , SMDF
The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene th
NCBI: 3084
UniProt: Q02297
Buffer: Reconstitute with 20mM Tris (pH8.0) and 150mM NaCl to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris (pH8.0), 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
Expression System: E. coli
Form: Lyophilized powder
Sequence: N-terminal His-Tag, Glu20~His242 (NP_001153467.1)
Application Notes: NRG1 (neuregulin-1) is a membrane glycoprotein that belongs to the neuregulin family and act on the EGFR family of receptors. It mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. It is reporte
SDS-PAGE analysis of GTX00417-pro Human Neuregulin-1 protein (active).
Cell proliferation effect of GTX00417-pro Human Neuregulin-1 protein (active) on MCF-7 cells. After incubation of Human Neuregulin-1 protein (active) for 72 hrs, cell proliferation was measured by Cell Counting Kit-8 (CCK-8). The ED50 for this effect is typically 5.240 to 9.112 ng/ml.
Cell proliferation effect of GTX00417-pro Human Neuregulin-1 protein (active).
(A) Unstimulated MCF-7 cells cultured in DMEM for 72hrs.
(B) MCF-7 cells cultured in DMEM, stimulated with 10 ng/ml NRG1 for 72hrs.
GTX00417-pro Image