Recombinant protein within human PACT aa 1-313 (O75569).
Conjugation:
Unconjugated
Alternative Names:
DYT16 antibody HSD14 antibody Interferon inducible double stranded RNA dependent protein kinase activator A antibody interferon-inducible double stranded RNA-dependent activator antibody Interferon-inducible double stranded RNA-dependent protein kinase a
Activates EIF2AK2/PKR in the absence of double-stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-