CBR-5884 is an active, selective inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 33 µM. CBR-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with high serine biosynthetic activity. C
Molecular Weight:
336.39
Purity:
99.02
CAS Number:
[681159-27-3]
Formula:
C14H12N2O4S2
Target:
Phosphoglycerate Dehydrogenase (PHGDH)
Application Notes:
Reference compound
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