AZD0156 is a potent, selective and orally active ATM inhibitor with an IC50 of 0.58 nM. AZD0156 inhibits the ATM-mediated signaling, prevents DNA damage checkpoint activation, disrupts DNA damage repair, and induces tumor cell apoptosis[1].
Molecular Weight:
461.56
Purity:
99.82
CAS Number:
[1821428-35-6]
Formula:
C26H31N5O3
Target:
Apoptosis,ATM/ATR
Application Notes:
Reference compound
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