Tomivosertib (eFT508) is a potent, highly selective, and orally active MNK1 and MNK2 inhibitor, with IC50s of 1-2 nM against both isoforms. Tomivosertib (eFT508) treatment leads to a dose-dependent reduction in eIF4E phosphorylation at serine 209 (IC50=2
Molecular Weight:
340.38
Purity:
99.92
CAS Number:
[1849590-01-7]
Formula:
C17H20N6O2
Target:
MNK,PD-1/PD-L1
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted