PT-262 is a potent ROCK inhibitor with an IC50 value of around 5 µM. PT-262 induces the loss of mitochondrial membrane potential and elevates the caspase-3 activation and apoptosis. PT-262 inhibits the ERK and CDC2 phosphorylation via a p53-independent p
Molecular Weight:
276.72
Purity:
99.21
CAS Number:
[86811-36-1]
Formula:
C14H13ClN2O2
Target:
Apoptosis,CDK,ERK,ROCK
Application Notes:
Reference compound
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