MK-4101 is a Smoothened (SMO) antagonist (IC50 of 1.1 µM for 293 cells ) and also a potent inhibitor of the hedgehog pathway (IC50 of 1.5 µM for mouse cells, IC50 of 1 µM for KYSE180 oesophageal cancer cells). MK-4101 has robust antitumor activity that i
Molecular Weight:
493.47
Purity:
98.31
CAS Number:
[935273-79-3]
Formula:
C24H24F5N5O
Target:
Apoptosis,Hedgehog,Smo
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted