O-Desmethyl gefitinib, CAS [[847949-49-9]]

Product Overview

• Article Name: O-Desmethyl gefitinib, CAS [[847949-49-9]]
• Biozol Catalog Number: MCE-HY-100064
• Supplier Catalog Number: HY-100064
• Alternative Catalog Number: MCE-HY-100064-50MG,MCE-HY-100064-10MMX1ML,MCE-HY-100064-25MG,MCE-HY-100064-10MG,MCE-HY-100064-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

O-Desmethyl gefitinib is an active metabolite of Gefitinib in human plasma. The formation of O-desmethyl gefitinib is dependent on CYP2D6 activity. O-desmethyl gefitinib inhibits EGFR with an IC50 of 36 nM in subcellular assays[1][2].

Product Properties

• Molecular Weight: 432.88
• Purity: 99.4
• CAS Number: [847949-49-9]
• Formula: C21H22ClFN4O3
• Target: EGFR

Application Notes

• Application Notes: Reference compound