DM1-SMe is an unconjugated form of the Maytansinoid in IMGN901. DM1-SMe is about 3-10-fold more potent than the parent agent Maytansine, with IC50s ranging from 0.003 to 0.01 nM for DM1-SMe in a panel of human tumor cell lines[1].
Molecular Weight:
784.38
Purity:
98.16
CAS Number:
[138148-68-2]
Formula:
C36H50ClN3O10S2
Target:
ADC Cytotoxin,Microtubule/Tubulin
Application Notes:
ADC Related
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