EAI045 is an allosteric and the fourth-generation inhibitor of mutant EGFR with IC50s of 1.9, 0.019, 0.19 and 0.002 µM for EGFR, EGFRL858R, EGFRT790M and EGFRL858R/T790M at 10 µM ATP, respectively.
Molecular Weight:
383.4
Purity:
99.08
CAS Number:
[1942114-09-1]
Formula:
C19H14FN3O3S
Target:
EGFR
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted