Splitomicin (Splitomycin) is a selective Sir2p inhibitor. Splitomicin inhibits NAD+-dependent HDAC activity of Sir2 protein. Splitomicin induces dose-dependent inhibition of HDAC in the yeast extract with an IC50 of 60 µM[1].
Molecular Weight:
198.22
Purity:
98.42
CAS Number:
[5690-03-9]
Formula:
C13H10O2
Target:
HDAC
Application Notes:
Reference compound
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