APS-2-79 is a KSR-dependent MEK antagonist. APS-2-79 inhibits ATPbiotin binding to KSR2 within the KSR2-MEK1 complexe with an IC50 of 120 nM. APS-2-79 makes the stabilization of the KSR inactive state antagonizes oncogenic Ras-MAPK signaling[1].
Molecular Weight:
387.43
Purity:
99.38
CAS Number:
[2002381-25-9]
Formula:
C23H21N3O3
Target:
MEK
Application Notes:
Reference compound
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