BDA-366 is a potent Bcl2 antagonist (Ki = 3.3 nM), binding Bcl2-BH4 domain with high affinity and selectivity. BDA-366 induces conformational change in Bcl2 that abrogates its antiapoptotic function, converting it from a survival molecule to a cell death
Molecular Weight:
423.50
CAS Number:
[1909226-00-1]
Formula:
C24H29N3O4
Target:
Bcl-2 Family
Application Notes:
Reference compound
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