GDC-0077 (RG6114) is a potent, orally available, and selective PI3Kalpha inhibitor (IC50=0.038 nM). GDC-0077 (RG6114) exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3. GDC-0077 (RG6114) is
Molecular Weight:
407.37
Purity:
99.85
CAS Number:
[2060571-02-8]
Formula:
C18H19F2N5O4
Target:
Apoptosis,PI3K
Application Notes:
Reference compound
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