Intoplicine (RP 60475), an antitumor derivative in the 7H-benzo[e]pyrido[4,3-b]indole series, is a DNA topoisomerase I and II inhibitor. Intoplicine strongly binds DNA (KA = 2 x 105 /M) and thereby increases the length of linear DNA[1][2].
Molecular Weight:
348.44
Purity:
98.36
CAS Number:
[125974-72-3]
Formula:
C21H24N4O
Target:
Topoisomerase
Application Notes:
Reference compound
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