SIRT6-IN-2 (Compound 5) is a selective SIRT6 inhibitor (IC50: 34 µM). SIRT6-IN-2 increases acetylation of H3K9 and increases glucose uptake in cultured cells. SIRT6-IN-2 also reduces T cell proliferation. SIRT6-IN-2 has immunosuppressive and chemosensiti
Molecular Weight:
366.32
Purity:
99.85
CAS Number:
[891002-11-2]
Formula:
C19H14N2O6
Target:
Sirtuin
Application Notes:
Reference compound
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