MKC8866, a salicylaldehyde analog, is a potent, selective IRE1 RNase inhibitor with an IC50 of 0.29 µM in human vitro. MKC8866 strongly inhibits Dithiothreitol-induced X-box-binding protein 1-spliced (XBP1s) expression with an EC50 of 0.52 µM and unstres
Molecular Weight:
361.35
Purity:
99.52
CAS Number:
[1338934-59-0]
Formula:
C18H19NO7
Target:
IRE1
Application Notes:
Reference compound
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