Pamapimod (Ro4402257) is a potent, selective and orally active p38 MAPK inhibitor with IC50s of 14 nM and 480 nM and Kis of 1.3 nM and 120 nM for p38alpha and p38beta, respectively. Pamapimod has no activity against p38delta or p38gamma isoforms. Pamapimod has the pote
Molecular Weight:
406.38
Purity:
99.92
CAS Number:
[449811-01-2]
Formula:
C19H20F2N4O4
Target:
Autophagy,p38 MAPK
Application Notes:
Reference compound
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