Theliatinib (Xiliertinib) is a potent, ATP-competitive, orally active and highly selective EGFR inhibitor with a Ki of 0.05 nM and an IC50 of 3 nM. Theliatinib has an IC50 of 22 nM for EGFR T790M/L858R mutant. Theliatinib shows >50-fold selectivity for E
Molecular Weight:
442.51
Purity:
99.77
CAS Number:
[1353644-70-8]
Formula:
C25H26N6O2
Target:
EGFR
Application Notes:
Reference compound
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