Milciclib (PHA-848125) is a potent, ATP-competitive and dual inhibitor of CDK and Tropomyosin receptor kinase (TRK), with IC50s of 45, 150, 160, 363, 398 nM and 53 nM for cyclin A/CDK2, cyclin H/CDK7, cyclin D1/CDK4, cyclin E/CDK2, cyclin B/CDK1 and TRKA
Molecular Weight:
460.57
Purity:
99.90
CAS Number:
[802539-81-7]
Formula:
C25H32N8O
Target:
Autophagy,CDK
Application Notes:
Reference compound
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