A 83-01 is a potent inhibitor of TGF-beta type I receptor ALK5 kinase, type I nodal receptor ALK4 and type I nodal receptor ALK7, with IC50s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5, ALK4 and ALK7, respectively[1].
Molecular Weight:
421.52
Purity:
99.41
CAS Number:
[909910-43-6]
Formula:
C25H19N5S
Target:
Organoid,TGF-beta Receptor
Application Notes:
Reference compound
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