Setileuton (MK-0633) is an inhibitor for 5-lipoxygenase, that inhibits the oxidation of arachidonic acid by recombinant human 5-LO, and the production of LTB4 in calcium ionophore-stimulated human whole blood, with IC50 of 3.9 and 52 nM, respectively[1].
Molecular Weight:
463.38
CAS Number:
[910656-27-8]
Formula:
C22H17F4N3O4
Target:
Lipoxygenase
Application Notes:
Reference compound
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