Pralatrexate is an antifolate and is a potent dihydrofolate reductasean (DHFR) inhibitor with a Ki of 13.4 pM. Pralatrexate is a substrate for folylpolyglutamate synthetase with improved cellular uptake and retention. Pralatrexate has antitumor activitie
Molecular Weight:
477.47
Purity:
99.23
CAS Number:
[146464-95-1]
Formula:
C23H23N7O5
Target:
Antifolate,Apoptosis
Application Notes:
Reference compound
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