LY2811376 is the first orally available non-peptidic beta-secretase (BACE1) inhibitor with IC50 of 239 nM-249 nM, that acts to decrease Abeta secretion with EC50 of 300 nM, and demonstrates to have 10-fold selectivity towards BACE1 over BACE2, and more than 50
Molecular Weight:
320.36
Purity:
99.89
CAS Number:
[1194044-20-6]
Formula:
C15H14F2N4S
Target:
Beta-secretase
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
