AMG-221 is an inhibitor of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) with a Ki of 12.8 nM in vitro biochemical scintillation proximity assay (SPA) and an IC50 of 10.1 nM in cell-based assays[1][2]. AMG-221 can be used for the research of type 2
Molecular Weight:
266.40
CAS Number:
[1095565-81-3]
Formula:
C14H22N2OS
Target:
11beta-HSD
Application Notes:
Reference compound
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