APC 366 is a selective inhibitor of mast cell tryptase (Ki=7.1 µM). APC 366 inhibits antigen-induced early asthmatic response (EAR), late asthmatic response (LAR), and bronchial hyperresponsiveness (BHR) in a sheep model of allergic asthma[1][2].
Molecular Weight:
440.50
CAS Number:
[158921-85-8]
Formula:
C22H28N6O4
Target:
Ser/Thr Protease
Application Notes:
Reference compound
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