Zamicastat (BIA 5-1058) is a dopamine beta-hydroxylase (DBH) inhibitor and can cross the blood-brain barrier (BBB) to cause central as well as peripheral effects. Zamicastat is also a concentration-dependent dual P-gp and BCRP inhibitor with IC50 values of
Molecular Weight:
401.47
Purity:
99.95
CAS Number:
[1080028-80-3]
Formula:
C21H21F2N3OS
Target:
BCRP,Dopamine beta-hydroxylase,P-glycoprotein
Application Notes:
Reference compound
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