PMX-53 (3D53) is a synthetic peptidic and a potent and orally active complement C5a receptor (CD88) antagonist with an IC50 of 20 nM. PMX-53 is also a low-affinity MrgX2 agonist that stimulates MrgX2-mediated mast cell degranulation. PMX-53 specifically
Molecular Weight:
896.09
Purity:
98.6
CAS Number:
[219639-75-5]
Formula:
C47H65N11O7
Target:
Complement System
Application Notes:
Reference compound
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