Niraparib (MK-4827) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity[1][2][3].
Molecular Weight:
320.39
Purity:
99.96
CAS Number:
[1038915-60-4]
Formula:
C19H20N4O
Target:
Apoptosis,PARP
Application Notes:
Reference compound
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