Niraparib (MK-4827) tosylate hydrate is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib tosylate hydrate leads to inhibition of repair of DNA damage, activates apoptosis and shows an
Molecular Weight:
510.61
Purity:
99.97
CAS Number:
[1613220-15-7]
Formula:
C26H30N4O5S
Target:
Apoptosis,PARP
Application Notes:
Reference compound
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