CJ-13,610, a nonredox-type 5-LO inhibitor, dose dependently suppresses 5-LO product formation in ionophore A23187-stimulated PMNL in the absence of exogenous AA with an IC50 of about 70 nM[1]. PMNL: polymorphonuclear leukocytes, AA: arachidonic acid
Molecular Weight:
393.5
Purity:
98.01
CAS Number:
[179420-17-8]
Formula:
C22H23N3O2S
Target:
Lipoxygenase
Application Notes:
Reference compound
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