T0901317 is an orally active and highly selective LXR agonist with an EC50 of 20 nM for LXRalpha[1]. T0901317 activates FXR with an EC50 of 5 µM[2]. T0901317 is RORalpha and RORgamma dual inverse agonist with Ki values of 132 nM and 51 nM, respectively[3]. T0901317
Molecular Weight:
481.33
Purity:
99.93
CAS Number:
[293754-55-9]
Formula:
C17H12F9NO3S
Target:
Apoptosis,FXR,LXR,ROR
Application Notes:
Reference compound
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