BIT-225 is an inhibitor for Vpu protein through block of Vpu ion channel, and thus inhibits the release of HIV-1, especially in monocyte-derived macrophages (EC50 is 2.25 µM), without significant cytotoxicity (TC50 is 284 µM)[1].
Molecular Weight:
293.32
Purity:
98.87
CAS Number:
[917909-71-8]
Formula:
C16H15N5O
Target:
HIV
Application Notes:
Reference compound
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