CH-0793076 (TP3076), a hexacyclic camptothecin analog, is active drug and major metabolite of TP300. CH-0793076 inhibits DNA topoisomerase I with an IC50 of 2.3 µM. CH-0793076 is efficacious against cells expressing BCRP (breast cancer resistance protein
Molecular Weight:
458.51
CAS Number:
[534605-78-2]
Formula:
C26H26N4O4
Target:
Topoisomerase
Application Notes:
Reference compound
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