ML154 (NCGC84) is a selective, brain-penetrant and non-peptide neuropeptide S receptor (NPSR) antagonist with a pA2 of 9.98. ML154 potently inhibits NPS-stimulated cellular calcium, cAMP, and ERK phosphorylation responses with IC50 values of 36.5 nM, 22.
Molecular Weight:
545.47
Purity:
98.02
CAS Number:
[1345964-89-7]
Formula:
C29H26BrN2PS
Target:
Neuropeptide Y Receptor
Application Notes:
Reference compound
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