RETRA is a mutant p53-dependent activator of p73 that suppresses mutant p53-bearing cancer cells. RETRA increases the expression level of p73, and a release of p73 from the blocking complex with mutant p53, which produces tumor-suppressor effects[1].
Molecular Weight:
269.34
Purity:
99.42
CAS Number:
[1036069-26-7]
Formula:
C11H11NO3S2
Target:
MDM-2/p53
Application Notes:
Reference compound
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