Trametinib (GSK1120212, JTP-74057) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib activates autophagy and induces apoptosis[1][2].
Molecular Weight:
615.39
Purity:
99.96
CAS Number:
[871700-17-3]
Formula:
C26H23FIN5O4
Target:
Apoptosis,Autophagy,MEK
Application Notes:
Reference compound
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