Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate),JTP-74057 (DMSO solvate)) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib (DMSO solvate) activates autophagy and induces apoptosis[1][2].
Molecular Weight:
693.53
Purity:
99.65
CAS Number:
[1187431-43-1]
Formula:
C28H29FIN5O5S
Target:
Apoptosis,MEK
Application Notes:
Reference compound
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