VU0409106 is a potent and selective mGlu5 negative allosteric modulator (NAM) with an IC50 of 24 nM. VU0409106 shows anxiolytic effects in rat models in a concentration-dependent manner. VU0409106 also penetrates the blood-brain barrier (BBB)[1][2].
Molecular Weight:
330.34
Purity:
99.76
CAS Number:
[1276617-62-9]
Formula:
C15H11FN4O2S
Target:
mGluR
Application Notes:
Reference compound
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