GN44028 is a potent and orally active hypoxia inducible factor (HIF)-1alpha inhibitor, with an IC50 of 14 nM. GN44028 inhibits hypoxia-induced HIF-1alpha transcriptional activity without suppressing HIF-1alpha mRNA expression, HIF-1alpha protein accumulation, or HIF-1alpha/
Molecular Weight:
305.33
Purity:
99.48
CAS Number:
[1421448-26-1]
Formula:
C18H15N3O2
Target:
HIF/HIF Prolyl-Hydroxylase
Application Notes:
Reference compound
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