Apcin, a ligand of Cdc20, is a potent and competitive anaphase-promoting complex/cyclosome (APC/C(Cdc20)) E3 ligase activity inhibitor. Apcin competitively inhibits APC/C-dependent ubiquitylation by binding to Cdc20 and preventing substrate recognition.
Molecular Weight:
438.65
Purity:
99.71
CAS Number:
[300815-04-7]
Formula:
C13H14Cl3N7O4
Target:
APC
Application Notes:
Reference compound
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