CU-T12-9 is a specific TLR1/2 agonist with EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay. CU-T12-9 activates both the innate and the adaptive immune systems. CU-T12-9 selectively activates the TLR1/2 heterodimer, not TLR2/6. CU-T12-9 signals through NF-kappaB
Molecular Weight:
362.31
Purity:
98.94
CAS Number:
[1821387-73-8]
Formula:
C17H13F3N4O2
Target:
Toll-like Receptor (TLR)
Application Notes:
Reference compound
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