PKI-179 hydrochloride is a potent and orally active dual PI3K/mTOR inhibitor, with IC50s of 8 nM, 24 nM, 74 nM, 77 nM, and 0.42 nM for PI3K-alpha, PI3K-beta, PI3K-gamma, PI3K-delta and mTOR, respectively. PKI-179 hydrochloride also exhibits activity over E545K and H104
Molecular Weight:
525.00
Purity:
98.11
CAS Number:
[1463510-35-1]
Formula:
C25H29ClN8O3
Target:
mTOR,PI3K
Application Notes:
Reference compound
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