AMG0347 is a transient receptor potential type V1 receptor antagonist. AMG0347 inhibits activation of the rat TRPV1 channel by heat (IC50 = 0.2 nm), protons (IC50= 0.8 nm), or capsaicin (IC50 = 0.7 nm)[1].
Molecular Weight:
445.48
CAS Number:
[946615-43-6]
Formula:
C24H26F3N3O2
Target:
TRP Channel
Application Notes:
Reference compound
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