CHIC35, an analog of EX-527, is a potent and selective inhibitor of SIRT1 (IC50=0.124 µM). CHIC35 shows potential selective inhibition against SIRT1 over SIRT2 (IC50=2.8 µM) or SIRT3 (IC50>100 µM)[1]. CHIC35 has anti-inflammatory effects and can be used
Molecular Weight:
262.73
CAS Number:
[848193-72-6]
Formula:
C14H15ClN2O
Target:
Sirtuin
Application Notes:
Reference compound
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