JGB1741 (ILS-JGB-1741) is a potent and specific SIRT1 activity inhibitor with an IC50 of 15 µM. JGB1741 is a weak SIRT2 and SIRT3 inhibitor with an all IC50>100 µM. JGB1741 increases the acetylated p53 levels leading to p53-mediated apoptosis with modul
Molecular Weight:
440.56
Purity:
99.05
CAS Number:
[1256375-38-8]
Formula:
C27H24N2O2S
Target:
Apoptosis,Sirtuin
Application Notes:
Reference compound
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