mTOR inhibitor-2 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR inhibitor-2 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates[1].
Molecular Weight:
411.46
CAS Number:
[2219323-96-1]
Formula:
C23H21N7O
Target:
mTOR
Application Notes:
Reference compound
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